DRUG DISCOVERY AND COMPUTER DRUG DESIGN
| Author(s) | : | K.Gobalan, S.Ahamed John |
| Institution | : | PG and Research Department of Biotechnology, Jamal Mohamed College, Trichy 20 |
| Published In | : | Vol. 1, Issue 9 — September 2014 |
| Page No. | : | 100-107 |
| Domain | : | Engineering |
| Type | : | Research Paper |
| ISSN (Online) | : | 2348-4470 |
| ISSN (Print) | : | 2348-6406 |
Drug Discovery through computer drug design, a recent, very effective technique in modern arena. Now a day’sComputer Aided Drug Design (CADD) technologies are used in nanotechnology, molecular biology, computational biology andgenomic proteomic, biochemistry etc. The main benefit of the computer aided drug design is cost effective in research anddevelopment of drugs. There are wide ranges of software are used in computer aided drug design, Grid computing, windowbased general modeling software, PKUDDS for structure based drug design,, JAVA, Perl and Python, computer aided drugdesign as well as software including software libraries. There are different techniques used in computer aided drug designvisualization, homology, molecular dynamic, energy minimization molecular docking, QSAR etc. Computer aided drug design isapplicable in Cancer disease, transportation of drug to specific site in body, data collec tions and storages of organics andbiological. Conformational properties and energetic of small molecules and DNA cleavage, molecular diagnostics based onfluorescence’s are focusing using this technique.
K.Gobalan, S.Ahamed John, “DRUG DISCOVERY AND COMPUTER DRUG DESIGN”, International Journal of Advance Engineering and Research Development (IJAERD), Vol. 1, Issue 9, pp. 100-107, September 2014.
