DRUG DISCOVERY AND COMPUTER DRUG DESIGN

Abstract

Drug Discovery through computer drug design, a recent, very effective technique in modern arena. Now a day’s
Computer Aided Drug Design (CADD) technologies are used in nanotechnology, molecular biology, computational biology and
genomic proteomic, biochemistry etc. The main benefit of the computer aided drug design is cost effective in research and
development of drugs. There are wide ranges of software are used in computer aided drug design, Grid computing, window
based general modeling software, PKUDDS for structure based drug design,, JAVA, Perl and Python, computer aided drug
design as well as software including software libraries. There are different techniques used in computer aided drug design
visualization, homology, molecular dynamic, energy minimization molecular docking, QSAR etc. Computer aided drug design is
applicable in Cancer disease, transportation of drug to specific site in body, data collec tions and storages of organics and
biological. Conformational properties and energetic of small molecules and DNA cleavage, molecular diagnostics based on
fluorescence’s are focusing using this technique.