Biosynthesis and GCMS analysis of Zinc Oxide nanoparticles from Leaf extract of Curcuma neilgherrensis Wight
Keywords:
Curcuma neilgherrensis, Zinc Oxide Nanoparticles, Antibacterial activity, GCMS, Drug Discovery, FTIR, SEM, UV, XRD.Abstract
Biologically synthesized nanoparticles have been broadly using in the field of medicine. Research in
nanotechnology highlights the possibility of green chemistry pathways to produce technologically important
nanomaterials. In the present study, the objective was to study the synthesis and analyse the Zinc Oxide Nanoparticles
(ZnO NPs) from Curcuma neilgherrensis leaf extract. The samples were characterized by Ultra-Violet Spectroscopy
(UV), Fourier transform infrared spectroscopy (FTIR), Scanning Electron Microscopy (SEM), X-ray diffraction (XRD).
These ZnO NPs were evaluated for antibacterial activity. The maximum diameter of inhibition zones around the disk
used for Pseudomonas aeruginosa indicates the resistance to ZnO NPs followed by Escherichia coli. Among the five
bacterial species tested, the Pseudomonas aeuroginosa is more susceptible when compared with other three species. It is
concluded that the biological synthesis of ZnO NPs is very rapid, effortless, cost effective and eco-friendly and without
any side effects and ZnO NPs may be used for the preparation of antibacterial formulations against Pseudomonas
aeuroginosa. Different functional groups were found to be present signifying the presence of different compounds in the
extract. GC-MS analysis of the samples was carried out using Shimadzu Make QP-2010 with nonpolar 60 M RTX 5MS
Column.
